Ponatinib CAS NO.943319-70-8

We have been providing over 1000 products including molecular targeted anticancer drugs, cell signaling pathway inhibitors,

pharmaceutical intermediates, and heterocyclic compounds, and quality services including custom synthesis, transfer of new

drug patent and technology, technical cooperation, and process optimization.

Year Establishment: 2008

Location: At one of the largest National Technical Integrated Drug Discovery Platforms in the High-Tech Zone of Jinan City

Our company was founded by a core group of top overseas pharmaceutical chemists, medical scientists business

management experts

We have built up solid cooperation with over twenty oversea companies over one hundred domestic companies

since the foundation

Specifications:

Name  Ponatinib

Synonyms  AP 24534; 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide

Molecular Formula  C₂₉H₂₇F₃N₆O

Molecular Weight  532.56

CAS Registry Number  943319-70-8
 

Applications:

AP24534 is a novel potent,ally available small molecule multitargeted kinase inhibitwith IC50 of 0.37, 2, 1.5, 2.2, 1.1, 10.24 nM fnative pan-BCR-ABL, mutated form, VEGFR2, FGFR1, PDGFRα, mutant FLT3 phosphorylation LYN.