2-Pyridinecarboxamide, 4-[[[4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl]oxy]methyl]-N-met hyl-, dihydrochloride CAS NO.332013-28-2

We have been providing over 1000 products including molecular targeted anticancer drugs, cell signaling pathway inhibitors,

pharmaceutical intermediates, and heterocyclic compounds, and quality services including custom synthesis, transfer of new

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Year Establishment: 2008

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Specifications:

Name  2-Pyridinecarboxamide, 4-[[[4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl]oxy]methyl]-N-met hyl-, dihydrochloride

Synonyms Telatinib (BAY 57-9352)

CAS Registry Number  332013-28-2

Applications:

2-Pyridinecarboxamide, 4-[[[4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl]oxy]methyl]-N-met hyl-, dihydrochloride (CAS:332013-

28-2) is the intermediate of Telatinib (BAY 57-9352),which is anally available, potent multitargeted VEGFR-2, VEGFR-3, PDGFR-β c-Kit

tyrosine kinases inhibit with an IC50 of 19 nM fthe inhibition of VEGFR-2 autophosphorylation.