OSI 420 CAS NO.183320-51-6

We have been providing over 1000 products including molecular targeted anticancer drugs, cell signaling pathway inhibitors,

pharmaceutical intermediates, and heterocyclic compounds, and quality services including custom synthesis, transfer of new

drug patent and technology, technical cooperation, and process optimization.

Jinan Trio PharmaTech was founded by a core group of top overseas pharmaceutical chemists, Medical scientists and

business management experts, and is an enterprise of science and technology supported by the "Attracting High-Level

Talent Scheme" of Jinan government.

Jinan Trio PharmaTech Co., Ltd. 

Year Establishment: 2008

Location: We are located at one of the largest National Technical Integrated Drug Discovery Platforms in the High-Tech Zone of Jinan City

Our company was founded by a core group of top overseas pharmaceutical chemists, medical scientists business

management experts

We have built up solid cooperation with over twenty oversea companies over one hundred domestic companies

since the foundation

Specifications:

Name  Methyl 4-chloropicolinate

Synonyms  Methyl 4-chloropyridine-2-carboxylate; 4-Chloropyridine-2-carboxylic acid methyl ester

Molecular Formula  C₇H₆ClNO₂

Molecular Weight  171.58

CAS Registry Number  24484-93-3
  
 

Applications:

OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is anally active EGFR tyrosin kinase inhibitwith IC50 of 2 20 nM fthe inhibition of human EGFR EGFR autophosphorylation in tumcells.