Urea, N-[2-chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-is oxazolyl)-, monohydrochloride, monohydrate CAS NO.682745-41-1

We have been providing over 1000 products including molecular targeted anticancer drugs, cell signaling pathway inhibitors,

pharmaceutical intermediates, and heterocyclic compounds, and quality services including custom synthesis, transfer of new

drug patent and technology, technical cooperation, and process optimization.

Year Establishment: 2008

Location: At one of the largest National Technical Integrated Drug Discovery Platforms in the High-Tech Zone of Jinan City

Our company was founded by a core group of top overseas pharmaceutical chemists, medical scientists business

management experts

We have built up solid cooperation with over twenty oversea companies over one hundred domestic companies

since the foundation

Specifications:

Name  2,3-Bis[amino[(2-aminophenyl)thio]methylene]butanedinitrile

Synonyms  Bis[amino(o-aminophenylthio)methylene]succinonitrile; U 0126; UO 126
 

Molecular Formula  C₁₈H₁₆N₆S₂

Molecular Weight  380.49

CAS Registry Number  682745-41-1
 

Applications:

Tivozanib also known as AV-951 is anally bioavailable potent VEGFR-1, 2 3, c-Kit PDGFR inhibitwith IC50 of 0.21, 0.16,

0.24, 1.63 1.72 nM, respectively.