PKI 402 CAS NO.1173204-81-3

We have been providing over 1000 products including molecular targeted anticancer drugs, cell signaling pathway inhibitors,

pharmaceutical intermediates, and heterocyclic compounds, and quality services including custom synthesis, transfer of new

drug patent and technology, technical cooperation, and process optimization.

Year Establishment: 2008

Location: At one of the largest National Technical Integrated Drug Discovery Platforms in the High-Tech Zone of Jinan City

Our company was founded by a core group of top overseas pharmaceutical chemists, medical scientists business

management experts

We have built up solid cooperation with over twenty oversea companies over one hundred domestic companies

since the foundation

Specifications:

Name  PKI 402

Synonyms  1-[4-[3-Ethyl-7-(morpholin-4-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]phenyl]-3-[4-[(4-methylpiperazin-1-yl)carbonyl]phenyl]urea

Molecular Formula  C₂₉H₃₄N₁₀O₃

Molecular Weight  570.65

CAS Registry Number  1173204-81-3
 

Applications:

Aive, reversible ATP-competitive Class I PI3K inhibitor. PI3Kα, IC50=1 nM; PI3Kβ, IC50=7 nM; PI3Kγ, IC50=16 nM; PI3Kδ, IC50=14 nM.