PP121 CAS NO.1092788-83-4

We have been providing over 1000 products including molecular targeted anticancer drugs, cell signaling pathway inhibitors,

pharmaceutical intermediates, and heterocyclic compounds, and quality services including custom synthesis, transfer of new

drug patent and technology, technical cooperation, and process optimization.

Year Establishment: 2008

Location: At one of the largest National Technical Integrated Drug Discovery Platforms in the High-Tech Zone of Jinan City

Our company was founded by a core group of top overseas pharmaceutical chemists, medical scientists business

management experts

We have built up solid cooperation with over twenty oversea companies over one hundred domestic companies

since the foundation

Specifications:

Name  PP 121

Synonyms  1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Molecular Formula  C₁₇H₁₇N₇

Molecular Weight  319.36

CAS Registry Number  1092788-83-4

Applications:

PP-121 is a multi-target inhibitof PDGFR, Hck, mTOR, VEGFR2, Src Abl with IC50 of 2 nM, 8 nM, 10 nM, 12 nM, 14 nM 18 nM, respectively, also inhibits DNA-PK with IC50 of 60 nM.